Marlon Mack’s injury has the potential to make two running backs usable in PPR leagues from Indy for Thursday Night Football. Jonathan Williams will be the favored waiver claim, and he did turn a screen pass into 31 yards in Week 11, but that was his only target. His teammate Nyheim Hines saw four targets and caught three after being targeted seven times the week before. Increased usage for Hines should be in the cards against Houston. 

WEEK 12 NON-PPR RANKINGS:Quarterback | Running back | Wide receiver | Tight end | D/ST | Kicker

We also saw another back likely to be a popular pickup, Derrius Guice, catch a short pass and turn it into big yardage (45-yard TD). That was one of just two targets for Guice, though, so don’t read too much into that for PPR purposes, although Guice should have no problem gaining yardage wherever he wants against Detroit in Week 12.

WEEK 12 PPR RANKINGS: Wide receiver | Tight end

PPR fantasy owners will have to deal with a number of significant RB absences due to bye, including Dalvin Cook, Melvin Gordon, Austin Ekeler, Damien Williams and Kenyan Drake. That means sleepers even further down these rankings could matter.

WEEK 12 DFS LINEUPS: FD cash | FD GPP | DK cash | DK GPP | Y! cash | Y! GPP

Kalen Ballage somehow managed 12 fantasy points in Week 11 due in part to his five catches despite gaining only 17 total yards, so he’s an option. Since taking over for Mark Walton, Ballage has nine catches. Miles Sanders continues to see passing-game usage for Philly and has a higher workload if Jordan Howard (stinger) is out again. Jaylen Samuels should see an uptick in value, too, assuming James Conner (shoulder) misses Week 12. And if you need a really deep dive, Lions’ RB J.D. McKissic has been targeted at least four times for three straight weeks.

MORE WEEK 12:Waiver pickups | FAAB planner | Stock watch | Snap counts | Fantasy playoff SOS

Reminder: Check back for frequent updates during the week. For standard league, individual RB analysis, click here.

MORE WEEK 12 DFS: Values | Stacks | Lineup Builder

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Week 12 Fantasy PPR Rankings: RBs

These rankings are for full-point PPR leagues.